MISSION

Loci is a Biophotonics instrumentation laboratory stemming from the Research activities of Kevin Eliceiri, Patti Keely, John White and other LOCI investigators. The mission of LOCI is to develop advanced optical and computational techniques for imaging and experimentally manipulating living specimens. New and improved imaging instrumentation and optical-based experimental techniques are being developed. These projects are driven by demands arising from the scien tific studies of external collaborators and the principal investigators and opportunities that arise with the emergence of new technology. Instrumentation development is undertaken in a form that is both accessible and beneficial to the scientific communi ty.

1. Development of new optical instrumentation to facilitate studi es of the dynamics of living specimens. Efforts are being focussed on the development of improved in vivo imaging techniques that provide significantly more information about a specimen than can currently be obtained.

2. Development of software for the capture and visualization of dynamic, three-dimensional cellular, or sub-cellular events.

3. Develop new caged probes and associated experimental methodologies that can be used for the spatially and temporally localized application of bioactive probes to living specimens.

4. I nvestigate the nature of phototoxicity and devise strategies for minimizing its effects.

 

For any questions about LOCI or its activities please contact the LOCI co- director, Kevin Eliceiri. LOCI is not a service microscopy center, for microscopy on the UW-Madison campus, please visit the University of Wisconsin Microscopy Portal

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